{ "_id": "6a1f1126b401979e7341d97b", "Package": "funkycells", "Title": "Functional Data Analysis for Multiplexed Cell Images", "Version": "1.1.1.9000", "Authors@R": "c(\nperson(\"Jeremy\", \"VanderDoes\", , \"jeremy.vanderdoes@gmail.com\",\nrole = c(\"aut\", \"cre\", \"cph\"),\ncomment = c(ORCID = \"0009-0001-9885-3073\")),\nperson(\"Jack\", \"Hywood\", role = \"aut\",\ncomment = c(ORCID = \"0000-0002-2028-2629\")),\nperson(\"Gregory\", \"Rice\", role = \"aut\")\n)", "Description": "Compare variables of interest between (potentially large\nnumbers of) spatial interactions and meta-variables. Spatial\nvariables are summarized using K, or other, functions, and\nprojected for use in a modified random forest model. The model\nallows comparison of functional and non-functional variables to\neach other and to noise, giving statistical significance to the\nresults. Included are preparation, modeling, and interpreting\ntools along with example datasets, as described in VanderDoes\net al., (2023) .", "License": "GPL (>= 3)", "URL": "https://github.com/jrvanderdoes/funkycells,\nhttps://jrvanderdoes.github.io/funkycells/", "BugReports": "https://github.com/jrvanderdoes/funkycells/issues", "VignetteBuilder": "knitr", "Config/testthat/edition": "3", "Encoding": "UTF-8", "LazyData": "true", "Roxygen": "list(markdown = TRUE)", "RoxygenNote": "7.2.3", "Config/pak/sysreqs": "make libicu-dev", "Repository": "https://jrvanderdoes.r-universe.dev", "Date/Publication": "2023-08-11 02:56:58 UTC", "RemoteUrl": "https://github.com/jrvanderdoes/funkycells", "RemoteRef": "HEAD", "RemoteSha": "53a257086f4d39c36069fbeb390d868e9e9bd475", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-17 08:03:06 UTC", "User": "root" }, "Author": "Jeremy VanderDoes [aut, cre, cph] (ORCID:\n),\nJack Hywood [aut] (ORCID: ),\nGregory Rice [aut]", "Maintainer": "Jeremy VanderDoes 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"Na_CD45_PC3", "Na_H3K9ac_PC1", "Na_H3K9ac_PC2", "Na_H3K9ac_PC3", "Na_PanKeratin_PC1", "Na_PanKeratin_PC2", "Na_PanKeratin_PC3", "Na_H3K27me3_PC1", "Na_H3K27me3_PC2", "Na_H3K27me3_PC3", "Na_phosphoS6_PC1", "Na_phosphoS6_PC2", "Na_phosphoS6_PC3", "Na_Keratin6_PC1", "Na_Keratin6_PC2", "Na_Keratin6_PC3", "Na_HLAClass1_PC1", "Na_HLAClass1_PC2", "Na_HLAClass1_PC3", "Na_Ta_PC1", "Na_Ta_PC2", "Na_Ta_PC3", "Na_Au_PC1", "Na_Au_PC2", "Na_Au_PC3", "Na_tumorYN_PC1", "Na_tumorYN_PC2", "Na_tumorYN_PC3", "Si_P_PC1", "Si_P_PC2", "Si_P_PC3", "Si_Ca_PC1", "Si_Ca_PC2", "Si_Ca_PC3", "Si_Fe_PC1", "Si_Fe_PC2", "Si_Fe_PC3", "Si_dsDNA_PC1", "Si_dsDNA_PC2", "Si_dsDNA_PC3", "Si_Vimentin_PC1", "Si_Vimentin_PC2", "Si_Vimentin_PC3", "Si_SMA_PC1", "Si_SMA_PC2", "Si_SMA_PC3", "Si_Background_PC1", "Si_Background_PC2", "Si_Background_PC3", "Si_CD4_PC1", "Si_CD4_PC2", "Si_CD4_PC3", "Si_CD16_PC1", "Si_CD16_PC2", "Si_CD16_PC3", "Si_EGFR_PC1", "Si_EGFR_PC2", "Si_EGFR_PC3", "Si_CD11c_PC1", "Si_CD11c_PC2", "Si_CD11c_PC3", "Si_CD68_PC1", "Si_CD68_PC2", "Si_CD68_PC3", "Si_CSF1R_PC1", "Si_CSF1R_PC2", "Si_CSF1R_PC3", "Si_CD8_PC1", "Si_CD8_PC2", "Si_CD8_PC3", "Si_CD3_PC1", "Si_CD3_PC2", "Si_CD3_PC3", "Si_CD45RO_PC1", "Si_CD45RO_PC2", "Si_CD45RO_PC3", "Si_Betacatenin_PC1", "Si_Betacatenin_PC2", "Si_Betacatenin_PC3", "Si_HLADR_PC1", "Si_HLADR_PC2", "Si_HLADR_PC3", "Si_CD45_PC1", "Si_CD45_PC2", "Si_CD45_PC3", "Si_H3K9ac_PC1", "Si_H3K9ac_PC2", "Si_H3K9ac_PC3", "Si_PanKeratin_PC1", "Si_PanKeratin_PC2", "Si_PanKeratin_PC3", "Si_H3K27me3_PC1", "Si_H3K27me3_PC2", "Si_H3K27me3_PC3", "Si_phosphoS6_PC1", "Si_phosphoS6_PC2", "Si_phosphoS6_PC3", "Si_Keratin6_PC1", "Si_Keratin6_PC2", "Si_Keratin6_PC3", "Si_HLAClass1_PC1", "Si_HLAClass1_PC2", "Si_HLAClass1_PC3", "Si_Ta_PC1", "Si_Ta_PC2", "Si_Ta_PC3", "Si_Au_PC1", "Si_Au_PC2", "Si_Au_PC3", "Si_tumorYN_PC1", "Si_tumorYN_PC2", "Si_tumorYN_PC3", "P_Ca_PC1", "P_Ca_PC2", "P_Ca_PC3", "P_Fe_PC1", "P_Fe_PC2", "P_Fe_PC3", "P_dsDNA_PC1", "P_dsDNA_PC2", "P_dsDNA_PC3", 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"Ca_H3K9ac_PC3", "Ca_PanKeratin_PC1", "Ca_PanKeratin_PC2", "Ca_PanKeratin_PC3", "Ca_H3K27me3_PC1", "Ca_H3K27me3_PC2", "Ca_H3K27me3_PC3", "Ca_phosphoS6_PC1", "Ca_phosphoS6_PC2", "Ca_phosphoS6_PC3", "Ca_Keratin6_PC1", "Ca_Keratin6_PC2", "Ca_Keratin6_PC3", "Ca_HLAClass1_PC1", "Ca_HLAClass1_PC2", "Ca_HLAClass1_PC3", "Ca_Ta_PC1", "Ca_Ta_PC2", "Ca_Ta_PC3", "Ca_Au_PC1", "Ca_Au_PC2", "Ca_Au_PC3", "Ca_tumorYN_PC1", "Ca_tumorYN_PC2", "Ca_tumorYN_PC3", "Fe_dsDNA_PC1", "Fe_dsDNA_PC2", "Fe_dsDNA_PC3", "Fe_Vimentin_PC1", "Fe_Vimentin_PC2", "Fe_Vimentin_PC3", "Fe_SMA_PC1", "Fe_SMA_PC2", "Fe_SMA_PC3", "Fe_Background_PC1", "Fe_Background_PC2", "Fe_Background_PC3", "Fe_CD4_PC1", "Fe_CD4_PC2", "Fe_CD4_PC3", "Fe_CD16_PC1", "Fe_CD16_PC2", "Fe_CD16_PC3", "Fe_EGFR_PC1", "Fe_EGFR_PC2", "Fe_EGFR_PC3", "Fe_CD11c_PC1", "Fe_CD11c_PC2", "Fe_CD11c_PC3", "Fe_CD68_PC1", "Fe_CD68_PC2", "Fe_CD68_PC3", "Fe_CSF1R_PC1", "Fe_CSF1R_PC2", "Fe_CSF1R_PC3", "Fe_CD8_PC1", "Fe_CD8_PC2", "Fe_CD8_PC3", "Fe_CD3_PC1", "Fe_CD3_PC2", "Fe_CD3_PC3", "Fe_CD45RO_PC1", "Fe_CD45RO_PC2", "Fe_CD45RO_PC3", "Fe_Betacatenin_PC1", "Fe_Betacatenin_PC2", "Fe_Betacatenin_PC3", "Fe_HLADR_PC1", "Fe_HLADR_PC2", "Fe_HLADR_PC3", "Fe_CD45_PC1", "Fe_CD45_PC2", "Fe_CD45_PC3", "Fe_H3K9ac_PC1", "Fe_H3K9ac_PC2", "Fe_H3K9ac_PC3", "Fe_PanKeratin_PC1", "Fe_PanKeratin_PC2", "Fe_PanKeratin_PC3", "Fe_H3K27me3_PC1", "Fe_H3K27me3_PC2", "Fe_H3K27me3_PC3", "Fe_phosphoS6_PC1", "Fe_phosphoS6_PC2", "Fe_phosphoS6_PC3", "Fe_Keratin6_PC1", "Fe_Keratin6_PC2", "Fe_Keratin6_PC3", "Fe_HLAClass1_PC1", "Fe_HLAClass1_PC2", "Fe_HLAClass1_PC3", "Fe_Ta_PC1", "Fe_Ta_PC2", "Fe_Ta_PC3", "Fe_Au_PC1", "Fe_Au_PC2", "Fe_Au_PC3", "Fe_tumorYN_PC1", "Fe_tumorYN_PC2", "Fe_tumorYN_PC3", "dsDNA_Vimentin_PC1", "dsDNA_Vimentin_PC2", "dsDNA_Vimentin_PC3", "dsDNA_SMA_PC1", "dsDNA_SMA_PC2", "dsDNA_SMA_PC3", "dsDNA_Background_PC1", "dsDNA_Background_PC2", "dsDNA_Background_PC3", "dsDNA_CD4_PC1", "dsDNA_CD4_PC2", "dsDNA_CD4_PC3", "dsDNA_CD16_PC1", "dsDNA_CD16_PC2", "dsDNA_CD16_PC3", "dsDNA_EGFR_PC1", "dsDNA_EGFR_PC2", "dsDNA_EGFR_PC3", "dsDNA_CD11c_PC1", "dsDNA_CD11c_PC2", "dsDNA_CD11c_PC3", "dsDNA_CD68_PC1", "dsDNA_CD68_PC2", "dsDNA_CD68_PC3", "dsDNA_CSF1R_PC1", "dsDNA_CSF1R_PC2", "dsDNA_CSF1R_PC3", "dsDNA_CD8_PC1", "dsDNA_CD8_PC2", "dsDNA_CD8_PC3", "dsDNA_CD3_PC1", "dsDNA_CD3_PC2", "dsDNA_CD3_PC3", "dsDNA_CD45RO_PC1", "dsDNA_CD45RO_PC2", "dsDNA_CD45RO_PC3", "dsDNA_Betacatenin_PC1", "dsDNA_Betacatenin_PC2", "dsDNA_Betacatenin_PC3", "dsDNA_HLADR_PC1", "dsDNA_HLADR_PC2", "dsDNA_HLADR_PC3", "dsDNA_CD45_PC1", "dsDNA_CD45_PC2", "dsDNA_CD45_PC3", "dsDNA_H3K9ac_PC1", "dsDNA_H3K9ac_PC2", "dsDNA_H3K9ac_PC3", "dsDNA_PanKeratin_PC1", "dsDNA_PanKeratin_PC2", "dsDNA_PanKeratin_PC3", "dsDNA_H3K27me3_PC1", "dsDNA_H3K27me3_PC2", "dsDNA_H3K27me3_PC3", "dsDNA_phosphoS6_PC1", "dsDNA_phosphoS6_PC2", "dsDNA_phosphoS6_PC3", "dsDNA_Keratin6_PC1", "dsDNA_Keratin6_PC2", "dsDNA_Keratin6_PC3", "dsDNA_HLAClass1_PC1", "dsDNA_HLAClass1_PC2", "dsDNA_HLAClass1_PC3", "dsDNA_Ta_PC1", "dsDNA_Ta_PC2", "dsDNA_Ta_PC3", "dsDNA_Au_PC1", "dsDNA_Au_PC2", "dsDNA_Au_PC3", "dsDNA_tumorYN_PC1", "dsDNA_tumorYN_PC2", "dsDNA_tumorYN_PC3", "Vimentin_SMA_PC1", "Vimentin_SMA_PC2", "Vimentin_SMA_PC3", "Vimentin_Background_PC1", "Vimentin_Background_PC2", "Vimentin_Background_PC3", "Vimentin_CD4_PC1", "Vimentin_CD4_PC2", "Vimentin_CD4_PC3", "Vimentin_CD16_PC1", "Vimentin_CD16_PC2", "Vimentin_CD16_PC3", "Vimentin_EGFR_PC1", "Vimentin_EGFR_PC2", "Vimentin_EGFR_PC3", "Vimentin_CD11c_PC1", "Vimentin_CD11c_PC2", "Vimentin_CD11c_PC3", "Vimentin_CD68_PC1", "Vimentin_CD68_PC2", "Vimentin_CD68_PC3", "Vimentin_CSF1R_PC1", "Vimentin_CSF1R_PC2", "Vimentin_CSF1R_PC3", "Vimentin_CD8_PC1", "Vimentin_CD8_PC2", "Vimentin_CD8_PC3", "Vimentin_CD3_PC1", "Vimentin_CD3_PC2", "Vimentin_CD3_PC3", "Vimentin_CD45RO_PC1", "Vimentin_CD45RO_PC2", "Vimentin_CD45RO_PC3", "Vimentin_Betacatenin_PC1", "Vimentin_Betacatenin_PC2", "Vimentin_Betacatenin_PC3", "Vimentin_HLADR_PC1", "Vimentin_HLADR_PC2", "Vimentin_HLADR_PC3", "Vimentin_CD45_PC1", "Vimentin_CD45_PC2", "Vimentin_CD45_PC3", "Vimentin_H3K9ac_PC1", "Vimentin_H3K9ac_PC2", "Vimentin_H3K9ac_PC3", "Vimentin_PanKeratin_PC1", "Vimentin_PanKeratin_PC2", "Vimentin_PanKeratin_PC3", "Vimentin_H3K27me3_PC1", "Vimentin_H3K27me3_PC2", "Vimentin_H3K27me3_PC3", "Vimentin_phosphoS6_PC1", "Vimentin_phosphoS6_PC2", "Vimentin_phosphoS6_PC3", "Vimentin_Keratin6_PC1", "Vimentin_Keratin6_PC2", "Vimentin_Keratin6_PC3", "Vimentin_HLAClass1_PC1", "Vimentin_HLAClass1_PC2", "Vimentin_HLAClass1_PC3", "Vimentin_Ta_PC1", "Vimentin_Ta_PC2", "Vimentin_Ta_PC3", "Vimentin_Au_PC1", "Vimentin_Au_PC2", "Vimentin_Au_PC3", "Vimentin_tumorYN_PC1", "Vimentin_tumorYN_PC2", "Vimentin_tumorYN_PC3", "SMA_Background_PC1", "SMA_Background_PC2", "SMA_Background_PC3", "SMA_CD4_PC1", "SMA_CD4_PC2", "SMA_CD4_PC3", "SMA_CD16_PC1", "SMA_CD16_PC2", "SMA_CD16_PC3", "SMA_EGFR_PC1", "SMA_EGFR_PC2", "SMA_EGFR_PC3", "SMA_CD11c_PC1", "SMA_CD11c_PC2", "SMA_CD11c_PC3", "SMA_CD68_PC1", "SMA_CD68_PC2", "SMA_CD68_PC3", "SMA_CSF1R_PC1", "SMA_CSF1R_PC2", "SMA_CSF1R_PC3", "SMA_CD8_PC1", "SMA_CD8_PC2", "SMA_CD8_PC3", "SMA_CD3_PC1", "SMA_CD3_PC2", "SMA_CD3_PC3", "SMA_CD45RO_PC1", "SMA_CD45RO_PC2", "SMA_CD45RO_PC3", "SMA_Betacatenin_PC1", "SMA_Betacatenin_PC2", "SMA_Betacatenin_PC3", "SMA_HLADR_PC1", "SMA_HLADR_PC2", "SMA_HLADR_PC3", "SMA_CD45_PC1", "SMA_CD45_PC2", "SMA_CD45_PC3", "SMA_H3K9ac_PC1", "SMA_H3K9ac_PC2", "SMA_H3K9ac_PC3", "SMA_PanKeratin_PC1", "SMA_PanKeratin_PC2", "SMA_PanKeratin_PC3", "SMA_H3K27me3_PC1", "SMA_H3K27me3_PC2", "SMA_H3K27me3_PC3", "SMA_phosphoS6_PC1", "SMA_phosphoS6_PC2", "SMA_phosphoS6_PC3", "SMA_Keratin6_PC1", "SMA_Keratin6_PC2", "SMA_Keratin6_PC3", "SMA_HLAClass1_PC1", "SMA_HLAClass1_PC2", "SMA_HLAClass1_PC3", "SMA_Ta_PC1", "SMA_Ta_PC2", "SMA_Ta_PC3", "SMA_Au_PC1", "SMA_Au_PC2", "SMA_Au_PC3", "SMA_tumorYN_PC1", "SMA_tumorYN_PC2", "SMA_tumorYN_PC3", "Background_CD4_PC1", "Background_CD4_PC2", "Background_CD4_PC3", "Background_CD16_PC1", "Background_CD16_PC2", "Background_CD16_PC3", "Background_EGFR_PC1", "Background_EGFR_PC2", "Background_EGFR_PC3", "Background_CD11c_PC1", "Background_CD11c_PC2", "Background_CD11c_PC3", "Background_CD68_PC1", "Background_CD68_PC2", "Background_CD68_PC3", "Background_CSF1R_PC1", "Background_CSF1R_PC2", "Background_CSF1R_PC3", "Background_CD8_PC1", "Background_CD8_PC2", "Background_CD8_PC3", "Background_CD3_PC1", "Background_CD3_PC2", "Background_CD3_PC3", "Background_CD45RO_PC1", "Background_CD45RO_PC2", "Background_CD45RO_PC3", "Background_Betacatenin_PC1", "Background_Betacatenin_PC2", "Background_Betacatenin_PC3", "Background_HLADR_PC1", "Background_HLADR_PC2", "Background_HLADR_PC3", "Background_CD45_PC1", "Background_CD45_PC2", "Background_CD45_PC3", "Background_H3K9ac_PC1", "Background_H3K9ac_PC2", "Background_H3K9ac_PC3", "Background_PanKeratin_PC1", "Background_PanKeratin_PC2", "Background_PanKeratin_PC3", "Background_H3K27me3_PC1", "Background_H3K27me3_PC2", "Background_H3K27me3_PC3", "Background_phosphoS6_PC1", "Background_phosphoS6_PC2", "Background_phosphoS6_PC3", "Background_Keratin6_PC1", "Background_Keratin6_PC2", "Background_Keratin6_PC3", "Background_HLAClass1_PC1", "Background_HLAClass1_PC2", "Background_HLAClass1_PC3", "Background_Ta_PC1", "Background_Ta_PC2", "Background_Ta_PC3", "Background_Au_PC1", "Background_Au_PC2", "Background_Au_PC3", "Background_tumorYN_PC1", "Background_tumorYN_PC2", "Background_tumorYN_PC3", "CD4_CD16_PC1", "CD4_CD16_PC2", "CD4_CD16_PC3", "CD4_EGFR_PC1", "CD4_EGFR_PC2", "CD4_EGFR_PC3", "CD4_CD11c_PC1", "CD4_CD11c_PC2", "CD4_CD11c_PC3", "CD4_CD68_PC1", "CD4_CD68_PC2", "CD4_CD68_PC3", "CD4_CSF1R_PC1", "CD4_CSF1R_PC2", "CD4_CSF1R_PC3", "CD4_CD8_PC1", "CD4_CD8_PC2", "CD4_CD8_PC3", "CD4_CD3_PC1", "CD4_CD3_PC2", "CD4_CD3_PC3", "CD4_CD45RO_PC1", "CD4_CD45RO_PC2", "CD4_CD45RO_PC3", "CD4_Betacatenin_PC1", "CD4_Betacatenin_PC2", "CD4_Betacatenin_PC3", "CD4_HLADR_PC1", "CD4_HLADR_PC2", "CD4_HLADR_PC3", "CD4_CD45_PC1", "CD4_CD45_PC2", "CD4_CD45_PC3", "CD4_H3K9ac_PC1", "CD4_H3K9ac_PC2", "CD4_H3K9ac_PC3", "CD4_PanKeratin_PC1", "CD4_PanKeratin_PC2", "CD4_PanKeratin_PC3", "CD4_H3K27me3_PC1", "CD4_H3K27me3_PC2", "CD4_H3K27me3_PC3", "CD4_phosphoS6_PC1", "CD4_phosphoS6_PC2", "CD4_phosphoS6_PC3", "CD4_Keratin6_PC1", "CD4_Keratin6_PC2", "CD4_Keratin6_PC3", "CD4_HLAClass1_PC1", "CD4_HLAClass1_PC2", "CD4_HLAClass1_PC3", "CD4_Ta_PC1", "CD4_Ta_PC2", "CD4_Ta_PC3", "CD4_Au_PC1", "CD4_Au_PC2", "CD4_Au_PC3", "CD4_tumorYN_PC1", "CD4_tumorYN_PC2", "CD4_tumorYN_PC3", "CD16_EGFR_PC1", "CD16_EGFR_PC2", "CD16_EGFR_PC3", "CD16_CD11c_PC1", "CD16_CD11c_PC2", "CD16_CD11c_PC3", "CD16_CD68_PC1", "CD16_CD68_PC2", "CD16_CD68_PC3", "CD16_CSF1R_PC1", "CD16_CSF1R_PC2", "CD16_CSF1R_PC3", "CD16_CD8_PC1", "CD16_CD8_PC2", "CD16_CD8_PC3", "CD16_CD3_PC1", "CD16_CD3_PC2", "CD16_CD3_PC3", "CD16_CD45RO_PC1", "CD16_CD45RO_PC2", "CD16_CD45RO_PC3", "CD16_Betacatenin_PC1", "CD16_Betacatenin_PC2", "CD16_Betacatenin_PC3", "CD16_HLADR_PC1", "CD16_HLADR_PC2", "CD16_HLADR_PC3", "CD16_CD45_PC1", "CD16_CD45_PC2", "CD16_CD45_PC3", "CD16_H3K9ac_PC1", "CD16_H3K9ac_PC2", "CD16_H3K9ac_PC3", "CD16_PanKeratin_PC1", "CD16_PanKeratin_PC2", "CD16_PanKeratin_PC3", "CD16_H3K27me3_PC1", "CD16_H3K27me3_PC2", "CD16_H3K27me3_PC3", "CD16_phosphoS6_PC1", "CD16_phosphoS6_PC2", "CD16_phosphoS6_PC3", "CD16_Keratin6_PC1", "CD16_Keratin6_PC2", "CD16_Keratin6_PC3", "CD16_HLAClass1_PC1", "CD16_HLAClass1_PC2", "CD16_HLAClass1_PC3", "CD16_Ta_PC1", "CD16_Ta_PC2", "CD16_Ta_PC3", "CD16_Au_PC1", "CD16_Au_PC2", "CD16_Au_PC3", "CD16_tumorYN_PC1", "CD16_tumorYN_PC2", "CD16_tumorYN_PC3", "EGFR_CD11c_PC1", "EGFR_CD11c_PC2", "EGFR_CD11c_PC3", "EGFR_CD68_PC1", "EGFR_CD68_PC2", "EGFR_CD68_PC3", "EGFR_CSF1R_PC1", "EGFR_CSF1R_PC2", "EGFR_CSF1R_PC3", "EGFR_CD8_PC1", "EGFR_CD8_PC2", "EGFR_CD8_PC3", "EGFR_CD3_PC1", "EGFR_CD3_PC2", "EGFR_CD3_PC3", "EGFR_CD45RO_PC1", "EGFR_CD45RO_PC2", "EGFR_CD45RO_PC3", "EGFR_Betacatenin_PC1", "EGFR_Betacatenin_PC2", "EGFR_Betacatenin_PC3", "EGFR_HLADR_PC1", "EGFR_HLADR_PC2", "EGFR_HLADR_PC3", "EGFR_CD45_PC1", "EGFR_CD45_PC2", "EGFR_CD45_PC3", "EGFR_H3K9ac_PC1", "EGFR_H3K9ac_PC2", "EGFR_H3K9ac_PC3", "EGFR_PanKeratin_PC1", "EGFR_PanKeratin_PC2", "EGFR_PanKeratin_PC3", "EGFR_H3K27me3_PC1", "EGFR_H3K27me3_PC2", "EGFR_H3K27me3_PC3", "EGFR_phosphoS6_PC1", "EGFR_phosphoS6_PC2", "EGFR_phosphoS6_PC3", "EGFR_Keratin6_PC1", "EGFR_Keratin6_PC2", "EGFR_Keratin6_PC3", "EGFR_HLAClass1_PC1", "EGFR_HLAClass1_PC2", "EGFR_HLAClass1_PC3", "EGFR_Ta_PC1", "EGFR_Ta_PC2", "EGFR_Ta_PC3", "EGFR_Au_PC1", "EGFR_Au_PC2", "EGFR_Au_PC3", "EGFR_tumorYN_PC1", "EGFR_tumorYN_PC2", "EGFR_tumorYN_PC3", "CD11c_CD68_PC1", "CD11c_CD68_PC2", "CD11c_CD68_PC3", "CD11c_CSF1R_PC1", "CD11c_CSF1R_PC2", "CD11c_CSF1R_PC3", "CD11c_CD8_PC1", "CD11c_CD8_PC2", "CD11c_CD8_PC3", "CD11c_CD3_PC1", "CD11c_CD3_PC2", "CD11c_CD3_PC3", "CD11c_CD45RO_PC1", "CD11c_CD45RO_PC2", "CD11c_CD45RO_PC3", "CD11c_Betacatenin_PC1", "CD11c_Betacatenin_PC2", "CD11c_Betacatenin_PC3", "CD11c_HLADR_PC1", "CD11c_HLADR_PC2", "CD11c_HLADR_PC3", "CD11c_CD45_PC1", "CD11c_CD45_PC2", "CD11c_CD45_PC3", "CD11c_H3K9ac_PC1", "CD11c_H3K9ac_PC2", "CD11c_H3K9ac_PC3", "CD11c_PanKeratin_PC1", "CD11c_PanKeratin_PC2", "CD11c_PanKeratin_PC3", "CD11c_H3K27me3_PC1", "CD11c_H3K27me3_PC2", "CD11c_H3K27me3_PC3", "CD11c_phosphoS6_PC1", "CD11c_phosphoS6_PC2", "CD11c_phosphoS6_PC3", "CD11c_Keratin6_PC1", "CD11c_Keratin6_PC2", "CD11c_Keratin6_PC3", "CD11c_HLAClass1_PC1", "CD11c_HLAClass1_PC2", "CD11c_HLAClass1_PC3", "CD11c_Ta_PC1", "CD11c_Ta_PC2", "CD11c_Ta_PC3", "CD11c_Au_PC1", "CD11c_Au_PC2", "CD11c_Au_PC3", "CD11c_tumorYN_PC1", "CD11c_tumorYN_PC2", "CD11c_tumorYN_PC3", "CD68_CSF1R_PC1", "CD68_CSF1R_PC2", "CD68_CSF1R_PC3", "CD68_CD8_PC1", "CD68_CD8_PC2", "CD68_CD8_PC3", "CD68_CD3_PC1", "CD68_CD3_PC2", "CD68_CD3_PC3", "CD68_CD45RO_PC1", "CD68_CD45RO_PC2", "CD68_CD45RO_PC3", "CD68_Betacatenin_PC1", "CD68_Betacatenin_PC2", "CD68_Betacatenin_PC3", "CD68_HLADR_PC1", "CD68_HLADR_PC2", "CD68_HLADR_PC3", "CD68_CD45_PC1", "CD68_CD45_PC2", "CD68_CD45_PC3", "CD68_H3K9ac_PC1", "CD68_H3K9ac_PC2", "CD68_H3K9ac_PC3", "CD68_PanKeratin_PC1", "CD68_PanKeratin_PC2", "CD68_PanKeratin_PC3", "CD68_H3K27me3_PC1", "CD68_H3K27me3_PC2", "CD68_H3K27me3_PC3", "CD68_phosphoS6_PC1", "CD68_phosphoS6_PC2", "CD68_phosphoS6_PC3", "CD68_Keratin6_PC1", "CD68_Keratin6_PC2", "CD68_Keratin6_PC3", "CD68_HLAClass1_PC1", "CD68_HLAClass1_PC2", "CD68_HLAClass1_PC3", "CD68_Ta_PC1", "CD68_Ta_PC2", "CD68_Ta_PC3", "CD68_Au_PC1", "CD68_Au_PC2", "CD68_Au_PC3", "CD68_tumorYN_PC1", "CD68_tumorYN_PC2", "CD68_tumorYN_PC3", "CSF1R_CD8_PC1", "CSF1R_CD8_PC2", "CSF1R_CD8_PC3", "CSF1R_CD3_PC1", "CSF1R_CD3_PC2", "CSF1R_CD3_PC3", "CSF1R_CD45RO_PC1", "CSF1R_CD45RO_PC2", "CSF1R_CD45RO_PC3", "CSF1R_Betacatenin_PC1", "CSF1R_Betacatenin_PC2", "CSF1R_Betacatenin_PC3", "CSF1R_HLADR_PC1", "CSF1R_HLADR_PC2", "CSF1R_HLADR_PC3", "CSF1R_CD45_PC1", "CSF1R_CD45_PC2", "CSF1R_CD45_PC3", "CSF1R_H3K9ac_PC1", "CSF1R_H3K9ac_PC2", "CSF1R_H3K9ac_PC3", "CSF1R_PanKeratin_PC1", "CSF1R_PanKeratin_PC2", "CSF1R_PanKeratin_PC3", "CSF1R_H3K27me3_PC1", "CSF1R_H3K27me3_PC2", "CSF1R_H3K27me3_PC3", "CSF1R_phosphoS6_PC1", "CSF1R_phosphoS6_PC2", "CSF1R_phosphoS6_PC3", "CSF1R_Keratin6_PC1", "CSF1R_Keratin6_PC2", "CSF1R_Keratin6_PC3", "CSF1R_HLAClass1_PC1", "CSF1R_HLAClass1_PC2", "CSF1R_HLAClass1_PC3", "CSF1R_Ta_PC1", "CSF1R_Ta_PC2", "CSF1R_Ta_PC3", "CSF1R_Au_PC1", "CSF1R_Au_PC2", "CSF1R_Au_PC3", "CSF1R_tumorYN_PC1", "CSF1R_tumorYN_PC2", "CSF1R_tumorYN_PC3", "CD8_CD3_PC1", "CD8_CD3_PC2", "CD8_CD3_PC3", "CD8_CD45RO_PC1", "CD8_CD45RO_PC2", "CD8_CD45RO_PC3", "CD8_Betacatenin_PC1", "CD8_Betacatenin_PC2", "CD8_Betacatenin_PC3", "CD8_HLADR_PC1", "CD8_HLADR_PC2", "CD8_HLADR_PC3", "CD8_CD45_PC1", "CD8_CD45_PC2", "CD8_CD45_PC3", "CD8_H3K9ac_PC1", "CD8_H3K9ac_PC2", "CD8_H3K9ac_PC3", "CD8_PanKeratin_PC1", "CD8_PanKeratin_PC2", "CD8_PanKeratin_PC3", "CD8_H3K27me3_PC1", "CD8_H3K27me3_PC2", "CD8_H3K27me3_PC3", "CD8_phosphoS6_PC1", "CD8_phosphoS6_PC2", "CD8_phosphoS6_PC3", "CD8_Keratin6_PC1", "CD8_Keratin6_PC2", "CD8_Keratin6_PC3", "CD8_HLAClass1_PC1", "CD8_HLAClass1_PC2", "CD8_HLAClass1_PC3", "CD8_Ta_PC1", "CD8_Ta_PC2", "CD8_Ta_PC3", "CD8_Au_PC1", "CD8_Au_PC2", "CD8_Au_PC3", "CD8_tumorYN_PC1", "CD8_tumorYN_PC2", "CD8_tumorYN_PC3", "CD3_CD45RO_PC1", "CD3_CD45RO_PC2", "CD3_CD45RO_PC3", "CD3_Betacatenin_PC1", "CD3_Betacatenin_PC2", "CD3_Betacatenin_PC3", "CD3_HLADR_PC1", "CD3_HLADR_PC2", "CD3_HLADR_PC3", "CD3_CD45_PC1", "CD3_CD45_PC2", "CD3_CD45_PC3", "CD3_H3K9ac_PC1", "CD3_H3K9ac_PC2", "CD3_H3K9ac_PC3", "CD3_PanKeratin_PC1", "CD3_PanKeratin_PC2", "CD3_PanKeratin_PC3", "CD3_H3K27me3_PC1", "CD3_H3K27me3_PC2", "CD3_H3K27me3_PC3", "CD3_phosphoS6_PC1", "CD3_phosphoS6_PC2", "CD3_phosphoS6_PC3", "CD3_Keratin6_PC1", "CD3_Keratin6_PC2", "CD3_Keratin6_PC3", "CD3_HLAClass1_PC1", "CD3_HLAClass1_PC2", "CD3_HLAClass1_PC3", "CD3_Ta_PC1", "CD3_Ta_PC2", "CD3_Ta_PC3", "CD3_Au_PC1", "CD3_Au_PC2", "CD3_Au_PC3", "CD3_tumorYN_PC1", "CD3_tumorYN_PC2", "CD3_tumorYN_PC3", "CD45RO_Betacatenin_PC1", "CD45RO_Betacatenin_PC2", "CD45RO_Betacatenin_PC3", "CD45RO_HLADR_PC1", "CD45RO_HLADR_PC2", "CD45RO_HLADR_PC3", "CD45RO_CD45_PC1", "CD45RO_CD45_PC2", "CD45RO_CD45_PC3", "CD45RO_H3K9ac_PC1", "CD45RO_H3K9ac_PC2", "CD45RO_H3K9ac_PC3", "CD45RO_PanKeratin_PC1", "CD45RO_PanKeratin_PC2", "CD45RO_PanKeratin_PC3", "CD45RO_H3K27me3_PC1", "CD45RO_H3K27me3_PC2", "CD45RO_H3K27me3_PC3", "CD45RO_phosphoS6_PC1", "CD45RO_phosphoS6_PC2", "CD45RO_phosphoS6_PC3", "CD45RO_Keratin6_PC1", "CD45RO_Keratin6_PC2", "CD45RO_Keratin6_PC3", "CD45RO_HLAClass1_PC1", "CD45RO_HLAClass1_PC2", "CD45RO_HLAClass1_PC3", "CD45RO_Ta_PC1", "CD45RO_Ta_PC2", "CD45RO_Ta_PC3", "CD45RO_Au_PC1", "CD45RO_Au_PC2", "CD45RO_Au_PC3", "CD45RO_tumorYN_PC1", "CD45RO_tumorYN_PC2", "CD45RO_tumorYN_PC3", "Betacatenin_HLADR_PC1", "Betacatenin_HLADR_PC2", "Betacatenin_HLADR_PC3", "Betacatenin_CD45_PC1", "Betacatenin_CD45_PC2", "Betacatenin_CD45_PC3", "Betacatenin_H3K9ac_PC1", "Betacatenin_H3K9ac_PC2", "Betacatenin_H3K9ac_PC3", "Betacatenin_PanKeratin_PC1", "Betacatenin_PanKeratin_PC2", "Betacatenin_PanKeratin_PC3", "Betacatenin_H3K27me3_PC1", "Betacatenin_H3K27me3_PC2", "Betacatenin_H3K27me3_PC3", "Betacatenin_phosphoS6_PC1", "Betacatenin_phosphoS6_PC2", "Betacatenin_phosphoS6_PC3", "Betacatenin_Keratin6_PC1", "Betacatenin_Keratin6_PC2", "Betacatenin_Keratin6_PC3", "Betacatenin_HLAClass1_PC1", "Betacatenin_HLAClass1_PC2", "Betacatenin_HLAClass1_PC3", "Betacatenin_Ta_PC1", "Betacatenin_Ta_PC2", "Betacatenin_Ta_PC3", "Betacatenin_Au_PC1", "Betacatenin_Au_PC2", "Betacatenin_Au_PC3", "Betacatenin_tumorYN_PC1", "Betacatenin_tumorYN_PC2", "Betacatenin_tumorYN_PC3", "HLADR_CD45_PC1", "HLADR_CD45_PC2", "HLADR_CD45_PC3", "HLADR_H3K9ac_PC1", "HLADR_H3K9ac_PC2", "HLADR_H3K9ac_PC3", "HLADR_PanKeratin_PC1", "HLADR_PanKeratin_PC2", "HLADR_PanKeratin_PC3", "HLADR_H3K27me3_PC1", "HLADR_H3K27me3_PC2", "HLADR_H3K27me3_PC3", "HLADR_phosphoS6_PC1", "HLADR_phosphoS6_PC2", "HLADR_phosphoS6_PC3", "HLADR_Keratin6_PC1", "HLADR_Keratin6_PC2", "HLADR_Keratin6_PC3", "HLADR_HLAClass1_PC1", "HLADR_HLAClass1_PC2", "HLADR_HLAClass1_PC3", "HLADR_Ta_PC1", "HLADR_Ta_PC2", "HLADR_Ta_PC3", "HLADR_Au_PC1", "HLADR_Au_PC2", "HLADR_Au_PC3", "HLADR_tumorYN_PC1", "HLADR_tumorYN_PC2", "HLADR_tumorYN_PC3", "CD45_H3K9ac_PC1", "CD45_H3K9ac_PC2", "CD45_H3K9ac_PC3", "CD45_PanKeratin_PC1", "CD45_PanKeratin_PC2", "CD45_PanKeratin_PC3", "CD45_H3K27me3_PC1", "CD45_H3K27me3_PC2", "CD45_H3K27me3_PC3", "CD45_phosphoS6_PC1", "CD45_phosphoS6_PC2", "CD45_phosphoS6_PC3", "CD45_Keratin6_PC1", "CD45_Keratin6_PC2", "CD45_Keratin6_PC3", "CD45_HLAClass1_PC1", "CD45_HLAClass1_PC2", "CD45_HLAClass1_PC3", "CD45_Ta_PC1", "CD45_Ta_PC2", "CD45_Ta_PC3", "CD45_Au_PC1", "CD45_Au_PC2", "CD45_Au_PC3", "CD45_tumorYN_PC1", "CD45_tumorYN_PC2", "CD45_tumorYN_PC3", "H3K9ac_PanKeratin_PC1", "H3K9ac_PanKeratin_PC2", "H3K9ac_PanKeratin_PC3", "H3K9ac_H3K27me3_PC1", "H3K9ac_H3K27me3_PC2", "H3K9ac_H3K27me3_PC3", "H3K9ac_phosphoS6_PC1", "H3K9ac_phosphoS6_PC2", "H3K9ac_phosphoS6_PC3", "H3K9ac_Keratin6_PC1", "H3K9ac_Keratin6_PC2", "H3K9ac_Keratin6_PC3", "H3K9ac_HLAClass1_PC1", "H3K9ac_HLAClass1_PC2", "H3K9ac_HLAClass1_PC3", "H3K9ac_Ta_PC1", "H3K9ac_Ta_PC2", "H3K9ac_Ta_PC3", "H3K9ac_Au_PC1", "H3K9ac_Au_PC2", "H3K9ac_Au_PC3", "H3K9ac_tumorYN_PC1", "H3K9ac_tumorYN_PC2", "H3K9ac_tumorYN_PC3", "PanKeratin_H3K27me3_PC1", "PanKeratin_H3K27me3_PC2", "PanKeratin_H3K27me3_PC3", "PanKeratin_phosphoS6_PC1", "PanKeratin_phosphoS6_PC2", "PanKeratin_phosphoS6_PC3", "PanKeratin_Keratin6_PC1", "PanKeratin_Keratin6_PC2", "PanKeratin_Keratin6_PC3", "PanKeratin_HLAClass1_PC1", "PanKeratin_HLAClass1_PC2", "PanKeratin_HLAClass1_PC3", "PanKeratin_Ta_PC1", "PanKeratin_Ta_PC2", "PanKeratin_Ta_PC3", "PanKeratin_Au_PC1", "PanKeratin_Au_PC2", "PanKeratin_Au_PC3", "PanKeratin_tumorYN_PC1", "PanKeratin_tumorYN_PC2", "PanKeratin_tumorYN_PC3", "H3K27me3_phosphoS6_PC1", "H3K27me3_phosphoS6_PC2", "H3K27me3_phosphoS6_PC3", "H3K27me3_Keratin6_PC1", "H3K27me3_Keratin6_PC2", "H3K27me3_Keratin6_PC3", "H3K27me3_HLAClass1_PC1", "H3K27me3_HLAClass1_PC2", "H3K27me3_HLAClass1_PC3", "H3K27me3_Ta_PC1", "H3K27me3_Ta_PC2", "H3K27me3_Ta_PC3", "H3K27me3_Au_PC1", "H3K27me3_Au_PC2", "H3K27me3_Au_PC3", "H3K27me3_tumorYN_PC1", "H3K27me3_tumorYN_PC2", "H3K27me3_tumorYN_PC3", "phosphoS6_Keratin6_PC1", "phosphoS6_Keratin6_PC2", "phosphoS6_Keratin6_PC3", "phosphoS6_HLAClass1_PC1", "phosphoS6_HLAClass1_PC2", "phosphoS6_HLAClass1_PC3", "phosphoS6_Ta_PC1", "phosphoS6_Ta_PC2", "phosphoS6_Ta_PC3", "phosphoS6_Au_PC1", "phosphoS6_Au_PC2", "phosphoS6_Au_PC3", "phosphoS6_tumorYN_PC1", "phosphoS6_tumorYN_PC2", "phosphoS6_tumorYN_PC3", "Keratin6_HLAClass1_PC1", "Keratin6_HLAClass1_PC2", "Keratin6_HLAClass1_PC3", "Keratin6_Ta_PC1", "Keratin6_Ta_PC2", "Keratin6_Ta_PC3", "Keratin6_Au_PC1", "Keratin6_Au_PC2", "Keratin6_Au_PC3", "Keratin6_tumorYN_PC1", "Keratin6_tumorYN_PC2", "Keratin6_tumorYN_PC3", "HLAClass1_Ta_PC1", "HLAClass1_Ta_PC2", "HLAClass1_Ta_PC3", "HLAClass1_Au_PC1", "HLAClass1_Au_PC2", "HLAClass1_Au_PC3", "HLAClass1_tumorYN_PC1", "HLAClass1_tumorYN_PC2", "HLAClass1_tumorYN_PC3", "Ta_Au_PC1", "Ta_Au_PC2", "Ta_Au_PC3", "Ta_tumorYN_PC1", "Ta_tumorYN_PC2", "Ta_tumorYN_PC3", "Au_tumorYN_PC1", "Au_tumorYN_PC2", "Au_tumorYN_PC3", "Na_Na_PC1", "Na_Na_PC2", "Na_Na_PC3", "Si_Si_PC1", "Si_Si_PC2", "Si_Si_PC3", "P_P_PC1", "P_P_PC2", "P_P_PC3", "Ca_Ca_PC1", "Ca_Ca_PC2", "Ca_Ca_PC3", "Fe_Fe_PC1", "Fe_Fe_PC2", "Fe_Fe_PC3", "dsDNA_dsDNA_PC1", "dsDNA_dsDNA_PC2", "dsDNA_dsDNA_PC3", "Vimentin_Vimentin_PC1", "Vimentin_Vimentin_PC2", "Vimentin_Vimentin_PC3", "SMA_SMA_PC1", "SMA_SMA_PC2", "SMA_SMA_PC3", "Background_Background_PC1", "Background_Background_PC2", "Background_Background_PC3", "CD4_CD4_PC1", "CD4_CD4_PC2", "CD4_CD4_PC3", "CD16_CD16_PC1", "CD16_CD16_PC2", "CD16_CD16_PC3", "EGFR_EGFR_PC1", "EGFR_EGFR_PC2", "EGFR_EGFR_PC3", "CD11c_CD11c_PC1", "CD11c_CD11c_PC2", "CD11c_CD11c_PC3", "CD68_CD68_PC1", "CD68_CD68_PC2", "CD68_CD68_PC3", "CSF1R_CSF1R_PC1", "CSF1R_CSF1R_PC2", "CSF1R_CSF1R_PC3", "CD8_CD8_PC1", "CD8_CD8_PC2", "CD8_CD8_PC3", "CD3_CD3_PC1", "CD3_CD3_PC2", "CD3_CD3_PC3", "CD45RO_CD45RO_PC1", "CD45RO_CD45RO_PC2", "CD45RO_CD45RO_PC3", "Betacatenin_Betacatenin_PC1", "Betacatenin_Betacatenin_PC2", "Betacatenin_Betacatenin_PC3", "HLADR_HLADR_PC1", "HLADR_HLADR_PC2", "HLADR_HLADR_PC3", "CD45_CD45_PC1", "CD45_CD45_PC2", "CD45_CD45_PC3", "H3K9ac_H3K9ac_PC1", "H3K9ac_H3K9ac_PC2", "H3K9ac_H3K9ac_PC3", "PanKeratin_PanKeratin_PC1", "PanKeratin_PanKeratin_PC2", "PanKeratin_PanKeratin_PC3", "H3K27me3_H3K27me3_PC1", "H3K27me3_H3K27me3_PC2", "H3K27me3_H3K27me3_PC3", "phosphoS6_phosphoS6_PC1", "phosphoS6_phosphoS6_PC2", "phosphoS6_phosphoS6_PC3", "Keratin6_Keratin6_PC1", "Keratin6_Keratin6_PC2", "Keratin6_Keratin6_PC3", "HLAClass1_HLAClass1_PC1", "HLAClass1_HLAClass1_PC2", "HLAClass1_HLAClass1_PC3", "Ta_Ta_PC1", "Ta_Ta_PC2", "Ta_Ta_PC3", "Au_Au_PC1", "Au_Au_PC2", 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